目录: Contents of Volume 1 A. Basic Principles Part I Structure and Function of the Liver Section I Embryology, Anatomy, and Histology 1 Embryonic Development 2 Gross Anatomy 3 Microscopic Anatomy Section II Fundamentals of Hepatic Physiology and Biochemistry 4 Hepatic Circulation 5 Hepatocellular Transport 6 Hepatic Metabolism 7 Formation and Secretion of Bile and Bilirubin Metabolism 8 Hepatic Biotransformation 9 Functional Heterogeneity and Metabolic Zonation 10 Liver Cell Hydration and Cell Function 11 The Liver as an Immune Organ 12 Aging and the Liver 13 Hepatic Regeneration Part II Pathophysiology and Morphology of Liver Injury Section III Causes and Mechanisms of Liver Injury 14 Free Radicals, Reactive Oxygen Species, Oxidative and Endoplasmic Reticulum Stress 15 Hypoxic Liver Injury 16 Reperfusion Injury 17 Drug-Induced and Toxic Liver Injury 18 Immune Mediated Liver Injury 19 Endotoxin Mediated Liver Injury 20 Cholestasis-Induced Liver Injury 21 Metal-Induced Liver Injury 22 Radiation-Induced Liver Damage Section IV Morphologic Patterns of Liver Injury 23 Liver Cell Degeneration and Cell Death 24 Cellular Adaptation, Intracellular Inclusions and Deposits 25 Necroinflammatory Reaction 26 Cholestatic Reaction 27 Granulomatous Reaction 28 Fibrogenic Reaction Section V Scoring Systems in Hepatology 29 Histopathological Scoring Systems 30 Clinical Scoring Systems B. Clinical Methods Part III Evaluation of the Patient with Hepatobiliary Disease Section VI History and Physical Examination 31 History 32 Symptoms 33 Physical Examination Section VII Laboratory Testing 34 Basic Laboratory Parameters 35 Tests of Liver Function 36 Autoantibodies Section VIII Hepatobiliary Imaging and Manometric Studies 37 Ultrasonography 38 Computed Tomography and Magnetic Resonance Imaging 39 Nuclear Imaging 40 Endoscopic Retrograde and Percutaneous Transhepatic Cholangiography 41 Cholangioscopy 42 Endoscopic Ultrasonography 43 Percutaneous Liver Biopsy 44 Transvenous Liver Biopsy 45 Laparoscopy 46 Measurement of Portal Pressure 47 Sphincter of Oddi Manometry Section IX Approaches to Common Hepatobiliary Problems 48 Approach to the Patient with Upper Abdominal Pain 49 Approach to the Patient with Abnormal Liver Enzymes 50 Approach to the Patient with Hepatomegaly 51 Approach to the Patient with Focal Liver Lesions 52 Approach to the Patient with Cholestasis and Jaundice 53 Approach to the Patient with Portal Hypertension 54 Approach to the Patient with Ascites Subject Index Contents of Volume 2 C. Hepatobiliary Diseases Part IV Diseases of the Liver Section X Developmental Anomalies 55 Malformations and Malpositions of the Liver 56 Bile Duct Anomalies 57 Liver Cysts and Polycystic Liver Disease 58 Vascular Anomalies Section XI Circulatory and Vascular Disorders 59 Hepatic Veins 60 Sinusoids 61 Portal Vein 62 Hepatic Arteries Section XII Infectious Liver Diseases 63 Viral Infections by Hepatotropic Viruses 64 Viral Infections by Nonhepatotropic Viruses 65 Bacterial Liver Abscess and Other Bacterial Infections 66 Amebic Liver Abscess and Other Protozoal Diseases 67 Helminthic Infections 68 Fungal Infections Section XIII Hepatobiliary Diseases in HIV-Infected Patients 69 Infections 70 Neoplastic Diseases 71 Drug-Induced Liver Injury Section XIV Autoimmune Liver Diseases 72 Autoimmune Hepatitis 73 Primary Biliary Cirrhosis 74 Autoimmune Cholangitis 75 Primary Sclerosing Cholangitis 76 Biliary Ductopenia (Vanishing Bile Duct Syndrome) 77 Autoimmune Overlap Syndromes Section XV Acute Liver Failure 78 Acute Liver Failure Section XVI Liver Cirrhosis and Sequelae 79 Liver Cirrhosis 80 Complications of Liver Cirrhosis Section XVII Genetic and Metabolic Liver Disorders 81 Wilson's Disease 82 Hereditary Hemochromatosis and Iron Overload 83 a1-Antitrypsin Deficiency 84 Porphyrias 85 Inherited Syndromes of Intrahepatic Cholestasis 86 Cystic Fibrosis 87 Amyloidosis 88 Alcoholic Liver Disease 89 Nonalcoholic Fatty Liver Disease 90 Other Metabolic Diseases: Tabellary Overview 91 Malnutrition and Nutrition in Liver Disease Section XVIII Drug-Induced and Toxic Liver Disease 92 Hepatic Drug Metabolism and Drug Toxicity 93 Drug- and Toxin-Induced Liver Injury Section XIX Granulomatous Liver Disease 94 Hepatic Granulomas 95 Sarcoidosis of the Liver Section XX Interaction Between the Liver and Other Organ Systems 96 Effects of Chronic Liver Disease on Other Organs: Tabellary Overview 97 Hepatic Involvement in Extrahepatic Disease: Tabellary Overview Section XXI Pregnancy-Specifi c Liver Diseases 98 Intrahepatic Cholestasis of Pregnancy 99 Acute Fatty Liver of Pregnancy 100 The Liver in Toxemia of Pregnancy Section XXII Primary Tumors of the Liver and Intrahepatic Bile Ducts 101 Benign Tumors 102 Malignant Tumors Section XXIII Liver Transplantation and Surgery in Liver Disease 103 Liver Transplantation: Indications, Preoperative Evaluation and Posttransplantation Management 104 Risk of Surgery in Patients with Liver Disease Section XXIV Gene Therapy 105 A Look to the Future: Gene Therapy in Liver Diseases Part V Diseases of the Gallbladder and Extrahepatic Bile Ducts Section XXV Anatomy, Histology and Physiology 106 Gross and Microscopic Anatomy 107 Physiology of the Gallbladder and the Extrahepatic Bile Ducts Section XXVI Developmental Anomalies 108 Anomalies of the Gallbladder and the Cystic Duct 109 Anomalies of the Extrahepatic Bile Ducts 110 Benign Strictures of the Extrahepatic Bile Ducts Section XXVII Motility Disorders 111 Motility Disorders of the Bile Ducts and Postcholecystectomy Syndrome Section XXVIII Gallstones 112 Gallbladder Stones 113 Bile Duct Stones Section XXIX Infectious Disorders 114 Biliary Infections Section XXX Tumors of the Gallbladder and Extrahepatic Bile Ducts 115 Benign Tumors 116 Malignant Tumors Subject Index
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