简介:  Volume 21(3); March 2012 Articles Enhanced meta-analysis of acetylcholine binding protein structures reveals conformational signatures of agonism in nicotinic receptors Spencer T Stober, Cameron F Abrams Protein Sci. 2012 March; 21(3): 307–317. Published online 2011 December 14. doi: 10.1002/pro.2016 PMCID: PMC3375432 Article PubReader PDF–1.2M Supplementary Material Glycine insertion at protease cleavage site of SNAP25 resists cleavage but enhances affinity for botulinum neurotoxin serotype A Mengfei Ho, Cheong-Hian Goh, Michael C Brothers, Shihua Wang, Ryan L Young, Yuxiang Ou, Juliana Nga-Man Lui, Marinos Kalafatis, Xiuwan Lan, Abigail E Wolf, Chad M Rienstra, Brenda A Wilson Protein Sci. 2012 March; 21(3): 318–326. Published online 2011 December 14. doi: 10.1002/pro.2017 PMCID: PMC3375433 Article PubReader PDF–1.3M Supplementary Material Modulation of the multistate folding of designed TPR proteins through intrinsic and extrinsic factors J J Phillips, Y Javadi, C Millership, E R G Main Protein Sci. 2012 March; 21(3): 327–338. Published online 2011 December 14. doi: 10.1002/pro.2018 PMCID: PMC3375434 Article PubReader PDF–1.1M Supplementary Material Critical differences in HIV-1 and HIV-2 protease specificity for clinical inhibitors Yunfeng Tie, Yuan-Fang Wang, Peter I Boross, Ting-Yi Chiu, Arun K Ghosh, Jozsef Tozser, John M Louis, Robert W Harrison, Irene T Weber Protein Sci. 2012 March; 21(3): 339–350. Published online 2012 January 11. doi: 10.1002/pro.2019 PMCID: PMC3375435 Article PubReader PDF–1.5M Expression of a soluble form of iodotyrosine deiodinase for active site characterization by engineering the native membrane protein from Mus musculus Jennifer M Buss, Patrick M McTamney, Steven E Rokita Protein Sci. 2012 March; 21(3): 351–361. Published online 2012 January 11. doi: 10.1002/pro.2020 PMCID: PMC3375436 Article PubReader PDF–1.3M Supplementary Material The role of the oligosaccharide binding cleft of rice BGlu1 in hydrolysis of cellooligosaccharides and in their synthesis by rice BGlu1 glycosynthase Salila Pengthaisong, Stephen G Withers, Buabarn Kuaprasert, Jisnuson Svasti, James R Ketudat Cairns Protein Sci. 2012 March; 21(3): 362–372. Published online 2012 January 11. doi: 10.1002/pro.2021 PMCID: PMC3375437 Article PubReader PDF–1.2M Supplementary Material Morin hydrate inhibits amyloid formation by islet amyloid polypeptide and disaggregates amyloid fibers Harris Noor, Ping Cao, Daniel P Raleigh Protein Sci. 2012 March; 21(3): 373–382. Published online 2012 January 11. doi: 10.1002/pro.2023 PMCID: PMC3375438 Article PubReader PDF–3.5M Supplementary Material Structure–function relationship of assimilatory nitrite reductases from the leaf and root of tobacco based on high-resolution structures Shogo Nakano, Misa Takahashi, Atsushi Sakamoto, Hiromichi Morikawa, Katsuo Katayanagi Protein Sci. 2012 March; 21(3): 383–395. Published online 2012 January 11. doi: 10.1002/pro.2025 PMCID: PMC3375439 Article PubReader PDF–2.0M Supplementary Material Prediction of protein–protein binding free energies Thom Vreven, Howook Hwang, Brian G Pierce, Zhiping Weng Protein Sci. 2012 March; 21(3): 396–404. Published online 2012 January 11. doi: 10.1002/pro.2027 PMCID: PMC3375440 Article PubReader PDF–878K Supplementary Material The impact of CRISPR repeat sequence on structures of a Cas6 protein–RNA complex Ruiying Wang, Han Zheng, Gan Preamplume, Yaming Shao, Hong Li Protein Sci. 2012 March; 21(3): 405–417. Published online 2012 January 11. doi: 10.1002/pro.2028 PMCID: PMC3375441 Article PubReader PDF–2.4M Supplementary Material An empirical phase diagram approach to investigate conformational stability of “second-generation” functional mutants of acidic fibroblast growth factor-1 Mohammad A Alsenaidy, Tingting Wang, Jae Hyun Kim, Sangeeta B Joshi, Jihun Lee, Michael Blaber, David B Volkin, C Russell Middaugh Protein Sci. 2012 March; 21(3): 418–432. Published online 2011 November 23. doi: 10.1002/pro.2008 PMCID: PMC3375442 Article PubReader PDF–1.7M Supplementary Material Probing protein stability and proteolytic resistance by loop scanning: A comprehensive mutational analysis Shoeb Ahmad, Virender Kumar, K Bhanu Ramanand, N Madhusudhana Rao Protein Sci. 2012 March; 21(3): 433–446. Published online 2012 January 13. doi: 10.1002/pro.2029 PMCID: PMC3375443 Article PubReader PDF–1.3M Supplementary Material For the Record Bidentate and tridentate metal-ion coordination states within ternary complexes of RB69 DNA polymerase Shuangluo Xia, Soo Hyun Eom, William H Konigsberg, Jimin Wang Protein Sci. 2012 March; 21(3): 447–451. Published online 2012 January 11. doi: 10.1002/pro.2026 PMCID: PMC3375444 Article PubReader PDF–1.0M Highlight In this Issue Protein Sci. 2012 March; 21(3): NA. doi: 10.1002/pro.2033 PMCID: PMC3375431 Article PubReader PDF–469K
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